Vanguard
· Added
Change
+1.6M
Date
Q1 2026
MI
| Investor | Type | Est. change | Change | Δ Own | Date | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
Vanguard
· Added
Change
+1.6M
Date
Q1 2026
|
Vanguard | Added· Q1 2026 | – | +1.6M | – | Q1 2026 | |||||
|
FMR LLC
· Added
Change
+1.3M
Δ Own
+204.0%
Date
Q1 2026
|
FMR LLC | Added· Q1 2026 | – | +1.3M | +204.0% | Q1 2026 | |||||
|
Tcg Crossover Management, LLC
· Added
Change
+1.0M
Date
Q1 2026
|
Tcg Crossover Management, LLC | Added· Q1 2026 | – | +1.0M | – | Q1 2026 | |||||
|
Frazier Life Sciences Management, L.P.
· Added
Change
+885K
Date
Q1 2026
|
Frazier Life Sciences Management, L.P. | Added· Q1 2026 | – | +885K | – | Q1 2026 | |||||
|
Janus Henderson Group PLC
· Added
Change
+881K
Date
Q1 2026
|
Janus Henderson Group PLC | Added· Q1 2026 | – | +881K | – | Q1 2026 | |||||
|
D. E. Shaw & Co., Inc.
· Reduced
Change
−781K
Δ Own
−82.3%
Date
Q1 2026
|
D. E. Shaw & Co., Inc. | Reduced· Q1 2026 | – | −781K | −82.3% | Q1 2026 | |||||
|
Capital World Investors
· New
Change
+724K
Date
Q1 2026
|
Capital World Investors | New· Q1 2026 | – | +724K | – | Q1 2026 | |||||
|
Eventide Asset Management, LLC
· Reduced
Change
−685K
Date
Q1 2026
|
Eventide Asset Management, LLC | Reduced· Q1 2026 | – | −685K | – | Q1 2026 | |||||
|
Paradigm Biocapital Advisors LP
· New
Change
+625K
Date
Q1 2026
|
Paradigm Biocapital Advisors LP | New· Q1 2026 | – | +625K | – | Q1 2026 | |||||
|
Polar Capital Holdings PLC
· Reduced
Change
−510K
Date
Q1 2026
|
Polar Capital Holdings PLC | Reduced· Q1 2026 | – | −510K | – | Q1 2026 | |||||
|
Baker Bros. Advisors LP
· New
Change
+446K
Date
Q1 2026
|
Baker Bros. Advisors LP | New· Q1 2026 | – | +446K | – | Q1 2026 | |||||
|
Two Sigma Investments, LP
· Added
Change
+386K
Δ Own
+99.4%
Date
Q1 2026
|
Two Sigma Investments, LP | Added· Q1 2026 | – | +386K | +99.4% | Q1 2026 | |||||
|
Octagon Capital Advisors LP
· New
Change
+339K
Date
Q1 2026
|
Octagon Capital Advisors LP | New· Q1 2026 | – | +339K | – | Q1 2026 | |||||
|
Ra Capital Management, L.P.
· New
Change
+319K
Date
Q1 2026
|
Ra Capital Management, L.P. | New· Q1 2026 | – | +319K | – | Q1 2026 | |||||
|
Arrowstreet Capital, Limited Partnership
· Reduced
Change
−305K
Date
Q1 2026
|
Arrowstreet Capital, Limited Partnership | Reduced· Q1 2026 | – | −305K | – | Q1 2026 | |||||
| Insider | Title | Type | Price | Qty | Value | Owned | ΔOwn | Trade date | Filed date | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
Peetz Christopher
· Director
4 operations
−$2.4M
|
Peetz Christopher | Director | 4 operations | $121.65–$124.79 | −20K | −$2.4M | 194K | −9.3% | Jul 6, 2026 | Jul 8, 2026 | |||||||||
|
Peetz Christopher
· Director
2 operations
0
|
Peetz Christopher | Director | 2 operations | $2.94 | 0 | – | 108K | – | Jul 6, 2026 | Jul 8, 2026 | |||||||||
|
Bjerkholt Eric
· Officer
4 operations
−$611K
|
Bjerkholt Eric | Officer | 4 operations | $121.67–$124.94 | −5K | −$611K | 42K | −10.6% | Jul 6, 2026 | Jul 8, 2026 | |||||||||
|
Howe Jolanda
· Officer
Sell
−$327K
|
Howe Jolanda | Officer | Sell | $120.00 | −3K | −$327K | 3K | −46.6% | Jul 1, 2026 | Jul 2, 2026 | |||||||||
|
Howe Jolanda
· Officer
Sell
−$264K
|
Howe Jolanda | Officer | Sell | $101.95 | −3K | −$264K | 6K | – | Jun 17, 2026 | Jun 18, 2026 | |||||||||
|
Walbert Timothy P.
· Director
2 operations
6K
|
Walbert Timothy P. | Director | 2 operations | – | 6K | – | 2K | – | Jun 15, 2026 | Jun 17, 2026 | |||||||||
|
Cardon Lon
· Director
2 operations
6K
|
Cardon Lon | Director | 2 operations | – | 6K | – | 2K | – | Jun 15, 2026 | Jun 17, 2026 | |||||||||
|
Ramasastry Saira
· Director
2 operations
6K
|
Ramasastry Saira | Director | 2 operations | – | 6K | – | 2K | – | Jun 15, 2026 | Jun 17, 2026 | |||||||||
|
Fairey William
· Director
2 operations
6K
|
Fairey William | Director | 2 operations | – | 6K | – | 2K | – | Jun 15, 2026 | Jun 17, 2026 | |||||||||
|
Brege Laura
· Director
2 operations
6K
|
Brege Laura | Director | 2 operations | – | 6K | – | 2K | – | Jun 15, 2026 | Jun 17, 2026 | |||||||||
|
Heron Patrick J.
· Director
2 operations
6K
|
Heron Patrick J. | Director | 2 operations | – | 6K | – | 2K | – | Jun 15, 2026 | Jun 17, 2026 | |||||||||
|
Fischer Laurent
· Director
2 operations
6K
|
Fischer Laurent | Director | 2 operations | – | 6K | – | 2K | – | Jun 15, 2026 | Jun 17, 2026 | |||||||||
|
Grey Michael G.
· Director
2 operations
6K
|
Grey Michael G. | Director | 2 operations | – | 6K | – | 2K | – | Jun 15, 2026 | Jun 17, 2026 | |||||||||
|
Bjerkholt Eric
· CFO
2 operations
0
|
Bjerkholt Eric | CFO | 2 operations | $26.49 | 0 | – | 27K | – | Jun 9, 2026 | Jun 9, 2026 | |||||||||
|
Bjerkholt Eric
· CFO
3 operations
−$469K
|
Bjerkholt Eric | CFO | 3 operations | $92.84–$95.12 | −5K | −$469K | 45K | – | Jun 8, 2026 | Jun 9, 2026 | |||||||||
N
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296 reporting institutions disclosed MIRM position changes in the Q1 2026 snapshot.
For each manager, WhoBought compares accepted consecutive 13F share counts. Share change is current shares minus prior shares. Estimated dollar change is that signed share change multiplied by the split-adjusted quarter-mean close. The activity table on this page uses Q1 2026.
An investor crossing 5% of a share class generally files Schedule 13D for activist intent or Schedule 13G for a passive position. The technical form names appear here rather than in the activity rows.
Ownership and institutional activity come from SEC Form 13F filings. Insider activity comes from SEC Form 4, and large-shareholder activity from SEC Schedules 13D and 13G. FMP supplies price data only. Company logos use the local verified Parqet cache with one shared fallback.
Form 13F is a quarterly disclosure and is normally filed after the quarter ends. Every ownership and activity value therefore names its represented period; it is not presented as a live position.
A muted dash marks a missing table value. It means the filing omitted the value, comparable data is unavailable, or no prior position exists for comparison.