IO
| Investor | Type | Est. change | Change | Δ Own | Date | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
Two Sigma Advisers, LP
· Exited
−$241M
Change
−3.1M
Δ Own
−100.0%
Date
Q1 2026
|
Two Sigma Advisers, LP | Exited· Q1 2026 | −$241M | −3.1M | −100.0% | Q1 2026 | |||||
|
Bellevue Group AG
· Reduced
−$235M
Change
−3.0M
Date
Q1 2026
|
Bellevue Group AG | Reduced· Q1 2026 | −$235M | −3.0M | – | Q1 2026 | |||||
|
T. Rowe Price Investment Management, Inc.
· Reduced
−$233M
Change
−2.9M
Date
Q1 2026
|
T. Rowe Price Investment Management, Inc. | Reduced· Q1 2026 | −$233M | −2.9M | – | Q1 2026 | |||||
|
Citadel Advisors LLC
· Reduced
−$94M
Change
−1.2M
Δ Own
−55.8%
Date
Q1 2026
|
Citadel Advisors LLC | Reduced· Q1 2026 | −$94M | −1.2M | −55.8% | Q1 2026 | |||||
|
Nomura Holdings Inc
· Reduced
−$58M
Change
−735K
Date
Q1 2026
|
Nomura Holdings Inc | Reduced· Q1 2026 | −$58M | −735K | – | Q1 2026 | |||||
|
Tri Locum Partners LP
· Exited
−$44M
Change
−557K
Δ Own
−100.0%
Date
Q1 2026
|
Tri Locum Partners LP | Exited· Q1 2026 | −$44M | −557K | −100.0% | Q1 2026 | |||||
|
Barclays PLC
· Reduced
−$44M
Change
−553K
Date
Q1 2026
|
Barclays PLC | Reduced· Q1 2026 | −$44M | −553K | – | Q1 2026 | |||||
|
Polar Capital Holdings PLC
· Reduced
−$40M
Change
−504K
Date
Q1 2026
|
Polar Capital Holdings PLC | Reduced· Q1 2026 | −$40M | −504K | – | Q1 2026 | |||||
|
BNP Paribas Asset Management Holding S.A.
· Reduced
−$35M
Change
−445K
Date
Q1 2026
|
BNP Paribas Asset Management Holding S.A. | Reduced· Q1 2026 | −$35M | −445K | – | Q1 2026 | |||||
|
Amundi
· Reduced
−$34M
Change
−437K
Date
Q1 2026
|
Amundi | Reduced· Q1 2026 | −$34M | −437K | – | Q1 2026 | |||||
|
Jain Global LLC
· Reduced
−$26M
Change
−330K
Date
Q1 2026
|
Jain Global LLC | Reduced· Q1 2026 | −$26M | −330K | – | Q1 2026 | |||||
|
Arrowstreet Capital, Limited Partnership
· Reduced
−$26M
Change
−325K
Date
Q1 2026
|
Arrowstreet Capital, Limited Partnership | Reduced· Q1 2026 | −$26M | −325K | – | Q1 2026 | |||||
|
Norges
· Exited
−$25M
Change
−320K
Δ Own
−100.0%
Date
Q1 2026
|
Norges | Exited· Q1 2026 | −$25M | −320K | −100.0% | Q1 2026 | |||||
|
Td Asset Management Inc
· Reduced
−$19M
Change
−243K
Date
Q1 2026
|
Td Asset Management Inc | Reduced· Q1 2026 | −$19M | −243K | – | Q1 2026 | |||||
|
Vanguard
· Reduced
−$19M
Change
−242K
Date
Q1 2026
|
Vanguard | Reduced· Q1 2026 | −$19M | −242K | – | Q1 2026 | |||||
| Insider | Title | Type | Price | Qty | Value | Owned | ΔOwn | Trade date | Filed date | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
Reikes Peter N.
· Director
Grant (A)
3K
|
Reikes Peter N. | Director | Grant (A) | – | 3K | – | 3K | – | Jul 15, 2026 | Jul 17, 2026 | |||||||||
|
Hantson Ludwig
· Director
Grant (A)
3K
|
Hantson Ludwig | Director | Grant (A) | – | 3K | – | 3K | – | Jul 15, 2026 | Jul 17, 2026 | |||||||||
|
Herman Joan E.
· Director
2 operations
0
|
Herman Joan E. | Director | 2 operations | – | 0 | – | 2K | – | Jul 15, 2026 | Jul 17, 2026 | |||||||||
|
Berthelsen Spencer R.
· Director
2 operations
0
|
Berthelsen Spencer R. | Director | 2 operations | – | 0 | – | 2K | – | Jul 15, 2026 | Jul 17, 2026 | |||||||||
|
Bennett C. Frank
· Officer
2 operations
−$1.7M
|
Bennett C. Frank | Officer | 2 operations | $83.58–$85.46 | −21K | −$1.7M | 0 | – | Jul 7, 2026 | Jul 9, 2026 | |||||||||
|
Bennett C. Frank
· Officer
2 operations
0
|
Bennett C. Frank | Officer | 2 operations | – | 0 | – | 12K | – | Jul 7, 2026 | Jul 9, 2026 | |||||||||
|
Diaz Allene M.
· Director
Sell
−$864K
|
Diaz Allene M. | Director | Sell | $85.42 | −10K | −$864K | 4K | −72.6% | Jul 7, 2026 | Jul 9, 2026 | |||||||||
|
Diaz Allene M.
· Director
2 operations
0
|
Diaz Allene M. | Director | 2 operations | $47.11 | 0 | – | 0 | – | Jul 7, 2026 | Jul 9, 2026 | |||||||||
|
Kordasiewicz Holly B.
· Officer
Sell
−$31K
|
Kordasiewicz Holly B. | Officer | Sell | $84.30 | −362 | −$31K | 22K | −1.6% | Jul 7, 2026 | Jul 9, 2026 | |||||||||
|
Yang Michael J.
· Director
2 operations
8K
|
Yang Michael J. | Director | 2 operations | – | 8K | – | 9K | – | Jul 1, 2026 | Jul 6, 2026 | |||||||||
|
Loscalzo Joseph
· Director
2 operations
8K
|
Loscalzo Joseph | Director | 2 operations | – | 8K | – | 8K | – | Jul 1, 2026 | Jul 6, 2026 | |||||||||
|
Herman Joan E.
· Director
2 operations
8K
|
Herman Joan E. | Director | 2 operations | – | 8K | – | 8K | – | Jul 1, 2026 | Jul 6, 2026 | |||||||||
|
Klein Joseph III
· Director
2 operations
−$910K
|
Klein Joseph III | Director | 2 operations | $79.04–$79.45 | −12K | −$910K | 11K | −51.1% | Jul 1, 2026 | Jul 6, 2026 | |||||||||
|
Klein Joseph III
· Director
2 operations
0
|
Klein Joseph III | Director | 2 operations | $39.94 | 0 | – | 0 | – | Jul 1, 2026 | Jul 6, 2026 | |||||||||
|
Klein Joseph III
· Director
2 operations
8K
|
Klein Joseph III | Director | 2 operations | – | 8K | – | 16K | – | Jul 1, 2026 | Jul 6, 2026 | |||||||||
460 reporting institutions disclosed IONS position changes in the Q1 2026 snapshot.
For each manager, WhoBought compares accepted consecutive 13F share counts. Share change is current shares minus prior shares. Estimated dollar change is that signed share change multiplied by the split-adjusted quarter-mean close. The activity table on this page uses Q1 2026.
An investor crossing 5% of a share class generally files Schedule 13D for activist intent or Schedule 13G for a passive position. The technical form names appear here rather than in the activity rows.
Ownership and institutional activity come from SEC Form 13F filings. Insider activity comes from SEC Form 4, and large-shareholder activity from SEC Schedules 13D and 13G. FMP supplies price data only. Company logos use the local verified Parqet cache with one shared fallback.
Form 13F is a quarterly disclosure and is normally filed after the quarter ends. Every ownership and activity value therefore names its represented period; it is not presented as a live position.
A muted dash marks a missing table value. It means the filing omitted the value, comparable data is unavailable, or no prior position exists for comparison.